Subscribe to RSS
DOI: 10.1055/a-2724-4037
The Price of Paralysis: Analyzing the Direct Cost of Facial Rehabilitation after Vestibular Schwannoma Resection
Authors
Funding Information This study was performed without commercial sponsorship or support.
Abstract
Objective
To estimate the direct costs associated with facial nerve rehabilitation for patients with facial paralysis after vestibular schwannoma (VS) resection.
Study Design
Retrospective cohort study.
Setting
Academic tertiary referral center.
Participants
Patients treated sequentially between September 2016 and May 2021 who experienced any degree of facial nerve dysfunction after VS resection and received rehabilitative interventions.
Main Outcome Measure
Estimated costs calculated based on institutional billing data.
Results
A total of 15 patients (67% female, median age at surgery of 56 years) were identified. Of the patients 14 (93%) had tumors with cerebellopontine angle extension, with a median size of 20.7 mm (interquartile range [IQR] 13.8–23.5). The median House-Brackmann (HB) grade immediately after surgery was 6 (IQR 3–6), and the median HB grade at most recent evaluation was 5 (IQR 4–6) with a median follow-up of 29 months (IQR 17–44). A total of 11 patients (73%) underwent periocular procedures; 4 (27%) underwent extensive rehabilitative surgeries, including nerve transfer and static sling procedures; 5 (33%) underwent chemodenervation therapy; and 9 (60%) performed facial retraining therapy with treatment being initiated at a median of 6.2 months (IQR 3.2–9.3) after surgery. The median cost for all patients was $3,125 (IQR $1,120–14,843), with the median cost of extensive rehabilitative surgery being $15,970 (IQR $14,907–29,289).
Conclusion
The median cost associated with facial rehabilitation is relatively low at $3,125; however, this amount varies based on the type of procedures pursued and individual need. Ultimately, a dedicated team of specialists is required to appropriately manage postoperative facial dysfunction in a cost-effective manner.
Ethical Approval
The Ohio State University IRB Protocol #2019H0363.
Note
This study was presented as a poster at the American Academy of Otolaryngology–Head and Neck Surgery 2024 Annual Meeting and Oto Expo on September 30, 2024 in Miami, FL.
Publication History
Received: 28 July 2025
Accepted: 13 October 2025
Accepted Manuscript online:
17 October 2025
Article published online:
31 October 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
-
References
- 1 Macielak RJ, Wallerius KP, Lawlor SK. et al. Defining clinically significant tumor size in vestibular schwannoma to inform timing of microsurgery during wait-and-scan management: moving beyond minimum detectable growth. J Neurosurg 2021; 136 (05) 1289-1297
- 2 Torres R, Nguyen Y, Vanier A. et al. Multivariate analysis of factors influencing facial nerve outcome following microsurgical resection of vestibular schwannoma. Otolaryngol Head Neck Surg 2017; 156 (03) 525-533
- 3 Ren Y, MacDonald BV, Tawfik KO, Schwartz MS, Friedman RA. Clinical predictors of facial nerve outcomes after surgical resection of vestibular schwannoma. Otolaryngol Head Neck Surg 2021; 164 (05) 1085-1093
- 4 Killeen DE, Barnett SL, Mickey BE, Hunter JB, Isaacson B, Kutz Jr JW. The association of vestibular schwannoma volume with facial nerve outcomes after surgical resection. Laryngoscope 2021; 131 (04) E1328-E1334
- 5 Marinelli JP, Herberg HA, Moore LS. et al. Salvage microsurgery following failed primary radiosurgery in sporadic vestibular schwannoma. JAMA Otolaryngol Head Neck Surg 2024; 150 (04) 287-294
- 6 Sobieski C, Killeen DE, Barnett SL. et al. Facial nerve outcomes after vestibular schwannoma microsurgical resection in neurofibromatosis type 2. Otolaryngol Head Neck Surg 2021; 164 (04) 850-858
- 7 Carlson ML, Tveiten ØV, Driscoll CL. et al. What drives quality of life in patients with sporadic vestibular schwannoma?. Laryngoscope 2015; 125 (07) 1697-1702
- 8 Ishii LE, Nellis JC, Boahene KD, Byrne P, Ishii M. The importance and psychology of facial expression. Otolaryngol Clin North Am 2018; 51 (06) 1011-1017
- 9 Leong SC, Lesser TH. A national survey of facial paralysis on the quality of life of patients with acoustic neuroma. Otol Neurotol 2015; 36 (03) 503-509
- 10 Ryzenman JM, Pensak ML, Tew Jr JM. Facial paralysis and surgical rehabilitation: a quality of life analysis in a cohort of 1,595 patients after acoustic neuroma surgery. Otol Neurotol 2005; 26 (03) 516-521 , discussion 521
- 11 Kleiss IJ, Hohman MH, Susarla SM, Marres HAM, Hadlock TA. Health-related quality of life in 794 patients with a peripheral facial palsy using the FaCE Scale: a retrospective cohort study. Clin Otolaryngol 2015; 40 (06) 651-656
- 12 Volk GF, Granitzka T, Kreysa H, Klingner CM, Guntinas-Lichius O. Initial severity of motor and non-motor disabilities in patients with facial palsy: an assessment using patient-reported outcome measures. Eur Arch Otorhinolaryngol 2017; 274 (01) 45-52
- 13 Nellis JC, Ishii M, Byrne PJ, Boahene KDO, Dey JK, Ishii LE. Association among facial paralysis, depression, and quality of life in facial plastic surgery patients. JAMA Facial Plast Surg 2017; 19 (03) 190-196
- 14 Ishii L, Godoy A, Encarnacion CO, Byrne PJ, Boahene KDO, Ishii M. Not just another face in the crowd: society's perceptions of facial paralysis. Laryngoscope 2012; 122 (03) 533-538
- 15 Li MKK, Niles N, Gore S, Ebrahimi A, McGuinness J, Clark JR. Social perception of morbidity in facial nerve paralysis. Head Neck 2016; 38 (08) 1158-1163
- 16 Bogart K, Tickle-Degnen L, Ambady N. Communicating without the face: holistic perception of emotions of people with facial paralysis. Basic Appl Soc Psych 2014; 36 (04) 309-320
- 17 Ishii LE, Godoy A, Encarnacion CO, Byrne PJ, Boahene KDO, Ishii M. What faces reveal: impaired affect display in facial paralysis. Laryngoscope 2011; 121 (06) 1138-1143
- 18 Mehta RP, Hadlock TA. Botulinum toxin and quality of life in patients with facial paralysis. Arch Facial Plast Surg 2008; 10 (02) 84-87
- 19 Lindsay RW, Bhama P, Hadlock TA. Quality-of-life improvement after free gracilis muscle transfer for smile restoration in patients with facial paralysis. JAMA Facial Plast Surg 2014; 16 (06) 419-424
- 20 Makhdoom N, Chaudry AS, Wong ZY. The use of botulinum toxin to improve cosmesis in patients with facial asymmetry following facial palsy/synkinesis—a literature review. J Plast Reconstr Aesthet Surg 2025; 100: 187-204
- 21 Dey JK, Ishii M, Boahene KDO, Byrne PJ, Ishii LE. Changing perception: facial reanimation surgery improves attractiveness and decreases negative facial perception. Laryngoscope 2014; 124 (01) 84-90
- 22 Dey JK, Ishii M, Boahene KDO, Byrne PJ, Ishii LE. Facial reanimation surgery restores affect display. Otol Neurotol 2014; 35 (01) 182-187
- 23 Steinhäuser J, Volk GF, Thielker J. et al. Multidisciplinary care of patients with facial palsy: treatment of 1220 patients in a German facial nerve center. J Clin Med 2022; 11 (02) 427
- 24 Macielak RJ, Thao V, Borah BJ. et al. Lifetime cost and quality-adjusted life-years across management options for small- and medium-sized sporadic vestibular schwannoma. Otol Neurotol 2021; 42 (09) e1369-e1375
- 25 Scholte M, Hentschel MA, Hannink G. et al. In search of the most cost-effective monitoring strategy for vestibular schwannoma: a decision analytical modelling study. Clin Otolaryngol 2019; 44 (04) 525-533
- 26 Zygourakis CC, Oh T, Sun MZ, Barani I, Kahn JG, Parsa AT. Surgery is cost-effective treatment for young patients with vestibular schwannomas: decision tree modeling of surgery, radiation, and observation. Neurosurg Focus 2014; 37 (05) E8
- 27 Abou-Al-Shaar H, Azab MA, Karsy M. et al. Assessment of costs in open surgery and stereotactic radiosurgery for vestibular schwannomas. J Neurosurg 2018; 131 (02) 561-568
- 28 Koester SW, Dambrino Iv RJ, Bhamidipati A. et al. Cost of vestibular schwannoma treatment: a systematic review and meta-analysis. J Neurol Surg B Skull Base 2023; 85 (06) 659-665
- 29 Verma S, Anthony R, Tsai V, Taplin M, Rutka J. Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma. Clin Otolaryngol 2009; 34 (05) 438-446
- 30 Morrison D. Management of patients with acoustic neuromas: a Markov decision analysis. Laryngoscope 2010; 120 (04) 783-790
- 31 Gait C, Frew EJ, Martin TPC, Jowett S, Irving R. Conservative management, surgery and radiosurgery for treatment of vestibular schwannomas: a model-based approach to cost-effectiveness. Clin Otolaryngol 2014; 39 (01) 22-31
- 32 Koester SW, Bishay AE, Rogers JL. et al. Cost considerations for vestibular schwannoma screening and imaging: a systematic review. Neurosurg Rev 2024; 47 (01) 59
- 33 Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). American Academy of Otolaryngology-Head and Neck Surgery Foundation, INC. Otolaryngol Head Neck Surg 1995; 113 (03) 179-180
- 34 House JW, Brackmann DE. Facial nerve grading system. Otolaryngol Head Neck Surg 1985; 93 (02) 146-147
- 35 Baricich A, Cabrio C, Paggio R, Cisari C, Aluffi P. Peripheral facial nerve palsy: how effective is rehabilitation?. Otol Neurotol 2012; 33 (07) 1118-1126
- 36 Vaughan A, Gardner D, Miles A, Copley A, Wenke R, Coulson S. A systematic review of physical rehabilitation of facial palsy. Front Neurol 2020; 11: 222
- 37 Lindsay RW, Robinson M, Hadlock TA. Comprehensive facial rehabilitation improves function in people with facial paralysis: a 5-year experience at the Massachusetts Eye and Ear Infirmary. Phys Ther 2010; 90 (03) 391-397
- 38 Hernández Herrero D, Abdel Muti García E, López Araujo J, Alfonso Barrera E, Moraleda Pérez S. Cost of peripheral facial palsy treatment with botulinum toxin type A. J Plast Reconstr Aesthet Surg 2022; 75 (01) 271-277
- 39 Kim D, Jung B, Cho MU. et al. Analysis of medical services provided to patients with peripheral facial palsy in Korea: a descriptive, cross-sectional study of the health insurance review and assessment service national patient sample database. BMC Health Serv Res 2021; 21 (01) 1178
- 40 Su P, Ishii LE, Joseph A. et al. Societal value of surgery for facial reanimation. JAMA Facial Plast Surg 2017; 19 (02) 139-146
- 41 Rathi VK, Xiao R, Sethi RKV. Analyzing charge data systematically overestimates health care costs. JAMA Otolaryngol Head Neck Surg 2021; 147 (10) 921-922
- 42 Arora V, Moriates C, Shah N. The challenge of understanding health care costs and charges. AMA J Ethics 2015; 17 (11) 1046-1052
